The journey to find the most substantial Major League Baseball players that wore the number 33 on their uniforms starts by looking at who the Baseball Hall of Fame has in their hallowed halls. Enshrined number ones of professional baseball are:
- Roy Campanella
- Frank Robinson
- Enos Slaughter
- Eddie Murray
- Mike Piazza
- Harold Baines
- Larry Walker
Another telling clue to find the best is to see who has the MLB number 33 retired by their respective teams. This list of retired number 33s includes:
- Mike Scott Astros October 3, 1992
- Eddie Murray Orioles June 7, 1998
- Honus Wagner Pirates February 16, 1952
- Larry Walker Rockies September 25, 2021