The journey to find the most substantial Major League Baseball players that wore the number 27 on their uniforms starts by looking at who the Baseball Hall of Fame has in their hallowed halls. Enshrined number ones of professional baseball are:
- Lloyd Waner
- Earl Averill
- Joe Sewell
- Juan Marichal
- Ernie Lombardi
- Catfish Hunter
- Tommy Lasorda
- Don Sutton
- Carlton Fisk
- Frank Thomas
- Vladimir Guerrero
Another telling clue to find the best is to see who has the MLB number 27 retired by their respective teams. This list of retired number 27s includes:
- Carlton Fisk Red Sox September 4, 2000
- Catfish Hunter Athletics June 9, 1991
- Juan Marichal Giants July 10, 1983