Born in Pembroke, Ontario, in 1890, Cameron began his professional career in 1913 with the Toronto Blueshirts. His offensive talent quickly shone, scoring eight goals in his first season. He even earned the distinction of scoring the NHL's first-ever goals on December 19, 1917, although his team, then named the Toronto Arenas, ended up losing.

Beyond his goal-scoring abilities, Cameron revolutionized the role of the defenseman. Known for his powerful slapshot and aggressive rushing style, he challenged the perception of defensemen as purely defensive players. His offensive contributions were significant, with seasons boasting 18 and 17 goals, feats rarely seen from defensemen in his era.

Beyond individual achievements, Cameron played a crucial role in team success. He was part of three Stanley Cup victories - one with the Blueshirts in 1914 and two with the St. Patricks in 1922 and 1923. His leadership and determination on the ice were instrumental in these triumphs.

Despite his talent and impact, Cameron's career was tragically cut short. In 1928, he contracted tuberculosis and eventually died in 1953 at the age of 63. His legacy, however, lived on. In 1992, he was inducted into the Hockey Hall of Fame, a testament to his lasting impact on the game.